A calcium hydroxylapatite filler that delivers immediate structural lift and triggers months of new collagen growth — placed by a University of Miami-trained nurse practitioner who owns the practice.
Kelly Wolfe, MSN, FNP-BC built her injection practice around two principles other Miami Beach clinics don't always honor: the right molecule for the right indication, and the right hands placing it. Radiesse is one of the most under-explained products in aesthetics — half filler, half biostimulator, with a hyperdilute application most local providers still don't offer. Kelly does, and explains the difference at consultation.
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OWNER · UNIVERSITY OF MIAMI-TRAINED · FL APRN #11005134
Jawline, chin, pre-jowl, lateral cheek, temples, marionette lines, nasolabial folds. Hyperdilute: neck, décolleté, hands, knees, upper arms, buttocks.
45–75 minute appointment. Most patients return to errands the same hour, full activity the next day.
Immediate volume from carrier gel. Collagen-stimulated improvement continues over 3–6 months. Typical duration 12–18 months (24+ months for hyperdilute neck and body).
$800–$1,100 per 1.5 mL syringe. Most jawline plans use 2–4 syringes. Per-syringe pricing, in writing, before any injection.
Kelly Wolfe, MSN, APRN, FNP-BC — Florida APRN #11005134, University of Miami-trained. Every injection, every appointment.
1000 5th Street, Suite 414 — South of Fifth, Miami Beach 33139. $4/hr attached garage; free street parking nearby during business hours. 8 minutes from Brickell.
Radiesse both fills and rebuilds — its calcium hydroxylapatite microspheres provide immediate structural volume AND stimulate your own collagen production over the following 3–6 months. HA fillers like Juvéderm or Restylane only do the first half. That's why Radiesse outlasts HA at the jawline, hands, and lateral cheek, and why the result becomes more durable over time rather than fading uniformly.
Radiesse is calcium hydroxylapatite (CaHA) — microspheres of a mineral your body already makes, suspended in an aqueous carrier gel. When Kelly injects Radiesse, two things happen on different timelines. The gel provides immediate volume and lift at the moment of injection. Then, over the following 8–12 weeks, your fibroblasts respond to the microspheres as a scaffold and begin producing new type I and type III collagen around them. The gel is gradually metabolized away. What’s left is the new collagen — yours, biologically integrated into your tissue, not a filler “deposit.”
That mechanism matters for three kinds of Miami Beach patients in particular:
Radiesse is composed of CaHA microspheres roughly 25–45 microns in diameter, suspended in a sodium carboxymethylcellulose gel. CaHA is the same mineral that makes up the inorganic phase of your bones and teeth — meaning your immune system does not treat it as foreign, and the risk of allergic reaction is essentially nil.
Once injected, the microspheres act as a biologic scaffold. Fibroblasts in the surrounding tissue migrate toward the scaffold and begin laying down new collagen — predominantly type III initially, transitioning to the more durable type I over 3–6 months. The gel carrier resorbs in the first 8–12 weeks. The collagen remains.
CaHA MICROSPHERE DIAMETER
NEW COLLAGEN FULLY ESTABLISHED
FDA-APPROVED FOR FACIAL USE
Radiesse is used most often on the jawline, chin, lateral cheek, temples, and the back of the hands — areas where structural volume against bone or under firm skin produces durable contour. Hyperdilute Radiesse extends that to the neck, décolleté, knees, upper arms, and buttocks as a skin-quality biostimulator. It is not used on lips or tear troughs.
Radiesse's signature application. A defined jawline with sharp angles, lifted pre-jowl, and crisp definition along the mandibular border. Typically 2–4 syringes per session for a full jawline; results visible immediately, optimized at 3 months as new collagen builds.
A common request from patients considering rhinoplasty who turn out to need chin balance instead. Radiesse forward-projects the chin and lengthens the mandible visually, restoring lower-face proportion and improving profile balance without surgery.
For patients with mid-face hollowing where structural lift matters more than soft contour. Radiesse in the lateral cheek raises the entire mid-face envelope, softening nasolabial folds indirectly. For diffuse cheek volume restoration, Sculptra or HA filler is sometimes a better fit — Kelly will choose between them at consultation.
The temple hollow is one of the most overlooked aging signs — and one of the most stabilizing to correct. A small amount of Radiesse in the deep temple restores fullness above the lateral brow and supports a subtle, indirect brow lift. Excellent value: high impact, low syringe count.
Radiesse softens the marionette lines and deep nasolabial folds by rebuilding underlying structural support. For deeper, fixed folds with significant volume loss, Radiesse outperforms most HA fillers on longevity. For softer, more superficial lines, an HA option is often more appropriate. Kelly chooses based on tissue depth and motion.
Sun-aged Miami Beach necks and chests are exactly what hyperdilute Radiesse was designed for. Diluted with sterile saline and lidocaine, it spreads across the surface to trigger collagen and elastin remodeling — visibly tightening, smoothing crepe, and softening "necklace lines." A 2–3 session series; results build over 4–6 months and last 18–24+ months.
Radiesse is the only FDA-approved injectable specifically for hand rejuvenation. It restores volume over the metacarpals and triggers skin-quality improvement that softens visible tendons and veins. A single session usually does it; results last 12+ months. A favorite for patients whose faces look 38 but whose hands betray a different number.
Hyperdilute Radiesse for the buttocks improves skin-quality, softens cellulite dimpling, and provides modest contour refinement. It is not a substitute for a surgical BBL or for high-volume Sculptra protocols — it is a skin-tightening, biostimulating treatment that complements either, and stands alone well for patients seeking refinement rather than transformation. Multi-session series.
Want a deeper exploration of any of these areas — anatomy, dosing, recovery, expected results? Visit the linked area pages above. Each is built around what to expect at your face or body region, not just the product.
Radiesse is wrong for lips, tear troughs, and patients who change their aesthetic preferences frequently — it can't be dissolved if you change your mind. It's also a poor fit for very thin, highly animated skin (forehead, perioral lines) where the firm particle structure can show through. For those indications, HA filler is the right tool.
If you are not a Radiesse candidate, Kelly will tell you so at consultation — and walk you through the product that is right for your indication, whether that’s Sculptra, a specific HA filler, or a non-injectable option like medical microneedling or RF.
Standard Radiesse is engineered for focal volume. Hyperdilute Radiesse is the same product diluted with sterile saline and lidocaine, transformed into a spreadable liquid biostimulator. It is delivered across larger surface areas to trigger broad collagen and elastin remodeling, rather than to add focal volume.
For the sun-aged Miami Beach neck, the crepe-textured décolleté, the aging hands, the dimpled upper arm or buttock — hyperdilute Radiesse is one of the most powerful tools in the injection space. It is also one of the most under-offered. Many local providers still aren’t trained to dilute and deliver it correctly.
A typical series: 2–3 sessions spaced 4–6 weeks apart. Initial improvement visible by week 6; full collagen response established by 3–4 months after the final session. Results last 18–24+ months.
Radiesse to diluent ratio (area-dependent)
Choose by indication, not by brand name. The right tool depends on whether you want immediate volume or gradual rebuild, focal contour or diffuse remodeling, longevity or reversibility. The table below is how Kelly maps the choice.
| Radiesse | Sculptra | HA Filler (Juvéderm, Restylane, RHA) | |
|---|---|---|---|
| Active material | Calcium hydroxylapatite microspheres in carrier gel | Poly-L-lactic acid (PLLA) microparticles | Cross-linked hyaluronic acid |
| Mechanism | Immediate volume + collagen stimulation Both at once | Pure collagen stimulator (no immediate volume) | Direct volume from the HA gel (no biostimulation) |
| Onset of visible result | Immediate (from carrier gel) | 6–8 weeks (collagen build only) | Immediate |
| Final result settled | 3–6 months | 3–6 months after final session | 2 weeks |
| Duration | 12–18 months (24+ hyperdilute) | Up to 24 months Longest | 6–18 months by product |
| Reversible? | No | No | Yes (hyaluronidase) Only reversible option |
| Best clinical use | Jawline, chin, structural lift, hands, hyperdilute neck/body | Diffuse mid-face volume restoration, BBL, broad collagen rebuild | Lips, tear troughs, fine lines, any reversible-needed application |
| Typical Miami Beach cost | $800–$1,100 per 1.5 mL syringe | $900–$1,200 per vial (series of 2–4) | $700–$1,200 per syringe (varies by product) |
| Sessions to result | 1 (focal) · 2–3 (hyperdilute) | 2–4 across several months | 1 |
Most Miami Beach practices won’t publish a price. We do, because patients deserve to know what they are walking into. The ranges below reflect what Kelly actually charges as of 2026. Your written quote at consultation reflects your specific plan.
Per 1.5 mL syringe. Most jawline plans use 2–4 syringes per session.
Per session per area (e.g., full neck). Series of 2–3 sessions recommended.
Both hands, single session. Single FDA-approved injectable for hands.
What you pay for. Per-syringe pricing means your invoice reflects exactly what was opened and placed. There is no per-area surcharge, no opaque “treatment package,” no upcharge for cannula vs. needle. If two syringes accomplish what we planned with three, you pay for two.
How Miami Beach compares to the national average. Miami Beach pricing for Radiesse runs roughly 10–20% above the national average, reflecting the city’s overhead realities. Quotes meaningfully above the typical range we publish usually reflect Brickell or Bal Harbour rent rather than better outcomes — and the most transparent practices walk you through a written plan before any injection. We do. Read more on how we approach pricing for injectables generally.
South Florida Face and Body sits in Suite 414 at 1000 5th Street, at the southern tip of Miami Beach. From SoFi, Kelly draws Radiesse patients across the barrier islands, across the causeway to mainland Miami, and from as far south as Key Biscayne.
SoFi is one of the most accessible aesthetic locations in the city — close to the MacArthur Causeway for Brickell, Downtown, and Key Biscayne patients, and a clear straight shot up Collins or Indian Creek for Mid-Beach, Surfside, and Bal Harbour. Most patients arrive in under twenty minutes door-to-door.
1000 5th Street, Suite 414 · Miami Beach, FL 33139
Geography genuinely matters in Radiesse planning. A Sunset Harbour patient whose daily routine is built around outdoor activity has different jawline biomechanics than a Brickell finance executive who hasn’t sweated through a workout this quarter. A Key Biscayne patient whose hands have spent twenty years on a boat steering wheel has a different hand-rejuvenation conversation than a Mid-Beach patient whose hands have lived under spreadsheets. Kelly builds those daily-life specifics into your plan rather than running the same protocol across every face and body.
A Radiesse appointment runs 45–75 minutes depending on areas treated. The injection itself is typically 15–25 minutes. The rest of that time — the anatomical mapping, the plan review, photographs, topical numbing — is what makes the result.
Radiesse at South Florida Face and Body is a biostimulator conversation, not a checkout selection. Most Miami practices market Radiesse as “the calcium-based filler that lasts longer,” which misses what actually makes it work: it is a biological process unfolding over 12 weeks, not a deposit of gel. Kelly’s practice approaches Radiesse the way the science supports — selecting standard vs hyperdilute formulation based on tissue depth and goal, dosing for the structural answer rather than the syringe count, and tracking the collagen-build trajectory across the first three months when most of the durable result is being constructed.
Kelly Wolfe is a Florida-licensed Advanced Practice Registered Nurse (APRN #11005134) and board-certified Family Nurse Practitioner (FNP-BC), credentialed by the American Nurses Credentialing Center. She holds a Master of Science in Nursing from the University of Miami, plus a Master’s in Biochemistry from Missouri State University, where her graduate research focused on metabolism and the role of leptin and appetite-suppressing hormones. The biochemistry background is uncommonly relevant for biostimulator work. The CaHA microsphere-to-fibroblast cascade, the type III to type I collagen transition timing, the dilution chemistry that determines how hyperdilute Radiesse behaves when it crosses tissue planes — real clinical reasoning, not pamphlet-level summaries. She is also a Certified Functional Medicine Practitioner.
The continuity matters for Radiesse specifically because the result is still actively forming at 8 weeks, mature at 12 weeks, and refined at 6 months. The practitioner who injected the original session is the only one who can read whether the collagen response is tracking as expected or whether the next maintenance dose should be adjusted. Kelly is the person who places every syringe and the person who tracks the response across the full 12–18 month arc.
Same-week consultations available. South of Fifth, Miami Beach.
Kelly is the owner of South Florida Face and Body. A board-certified Family Nurse Practitioner trained at the University of Miami, she holds advanced degrees in nursing, biochemistry, and biology, with graduate research focused on metabolism and the role of leptin and appetite-suppressing hormones. She practices at the intersection of functional medicine and aesthetic injection — meaning the conversations in her treatment room often go beyond the syringe to consider sleep, hormones, metabolism, and inflammation as part of how your skin and face actually present.
Licensed as an Advanced Practice Registered Nurse in the State of Florida (APRN #11005134), Kelly brings more than three decades of experience in health, fitness, and clinical practice. She has performed aesthetic injections in South Florida for over a decade and has trained alongside the dermatology and plastic surgery community that built Miami’s aesthetic reputation.
She is the one who answers your text message. She is the one who calls the day after your injection.
From your first consultation through every follow-up, you’ll work directly with Kelly — one injector, one set of hands, one consistent plan.
Advanced practice registered nursing with a focus on family health and primary care.
Research focused on metabolism and the role of leptin and appetite-suppressing hormones.
Research with a strong foundation in human physiology, cellular biology, and biochemistry.
National certification in family practice and primary care.
Authorized to diagnose, treat, and prescribe medications in the State of Florida.
Advanced training in root-cause diagnostics, hormone optimization, metabolic health, and integrative wellness.
Over 30 years helping clients achieve sustainable health and wellness transformations.
"Kelly is amazing! She's incredibly knowledgeable and progressive when it comes to facial aesthetics. My Botox and filler results are natural, refreshed, and exactly what I was hoping for — never overdone."
"Kelly is the best! She truly listens to what her clients want and delivers exactly what you picture. My results are always natural and beautiful. I couldn't recommend her more!"
"I was on holiday in Miami and got the details for Kelly. Best Botox I have had. She advised my husband who had very sore facial skin with a new routine and has cleared up the problem. Would certainly recommend."
Common questions from Miami Beach patients considering Radiesse. If yours isn't covered here, Kelly is happy to answer directly — text or call.
Radiesse in Miami Beach typically ranges from $800 to $1,100 per 1.5 mL syringe. Most jawline or chin treatments require 2–4 syringes, putting a single session between roughly $1,600 and $4,400. Hyperdilute Radiesse for the neck or décolleté runs $1,200–$1,800 per area per session, with a recommended series of 2–3 sessions. Hand rejuvenation runs $1,400–$2,200 for both hands in a single session.
At South Florida Face and Body, every quote is in writing before injection, and you only pay for syringes actually used. Quotes meaningfully above the regional range often reflect Brickell or Bal Harbour overhead rather than better outcomes.
Radiesse results typically last 12 to 18 months for facial volumization. The initial volume is immediate from the carrier gel, but the longer-lasting effect comes from new collagen the body produces around the calcium hydroxylapatite microspheres over 3–6 months. Hyperdilute Radiesse for skin-quality applications (neck, décolleté, body) lasts 18–24+ months following a 2–3 session series.
Active Miami Beach lifestyles — daily outdoor training, frequent sun and salt exposure, heavier metabolisms common in fitness-focused patients — can shorten the duration slightly. Most patients in our practice plan a maintenance touch-up annually.
Both are biostimulators, meaning both trigger your body to produce new collagen rather than simply filling space. The difference is mechanism and timeline.
Radiesse (calcium hydroxylapatite) provides immediate volume from its carrier gel, plus continuous collagen stimulation. Results last 12–18 months. Best for structural lift in defined areas — jawline, chin, hands.
Sculptra (poly-L-lactic acid) provides no immediate volume. It builds collagen gradually across 2–4 sessions over several months, with the final result settling 3–6 months after your last session and lasting up to 24 months. Best for diffuse mid-face volume restoration over wider areas.
Many patients use both — Radiesse for structural definition (jawline, chin) and Sculptra for broad facial rejuvenation. A consultation determines fit.
Hyperdilute Radiesse is standard Radiesse mixed with extra sterile saline and lidocaine to create a thinner, more spreadable preparation. Rather than focal volume, it delivers as a liquid biostimulator across larger surface areas — neck, décolleté, hands, knees, upper arms, buttocks — to trigger collagen and elastin remodeling for skin tightening and skin-quality improvement.
The Miami Beach use case is obvious: sun-aged necks, crepe-textured chests, hands that have spent decades on the water. Hyperdilute Radiesse is one of the most powerful non-surgical tools available for these areas, and one of the most under-offered locally — many providers still aren’t trained to dilute and place it correctly.
Typical protocol: 2–3 sessions spaced 4–6 weeks apart. Initial improvement visible by week 6; full collagen response established 3–4 months after the final session. Results last 18–24+ months.
Radiesse is most commonly used in deep structural areas: jawline, chin, pre-jowl, lateral cheek, temples, marionette lines, and nasolabial folds. It is also FDA-approved for the back of the hands. It is not typically used in lips, tear troughs, or other highly mobile, superficial areas — those are better served by hyaluronic acid fillers that can be dissolved if needed.
Hyperdilute Radiesse expands the menu off the face entirely — neck, décolleté, knees, arms, buttocks. Each region has its own protocol; the treatment areas grid above walks through what to expect at each.
For non-surgical buttock enhancement, both have a place. Hyperdilute Radiesse is preferred when the goal is skin-quality improvement, modest contour refinement, and softening of cellulite dimpling — it tightens, lifts, and improves texture. Sculptra is preferred when the goal is meaningful volume restoration over multiple sessions.
A consultation determines which tool — or which combination — fits your goal, your anatomy, and your budget. Anyone promising a surgical-BBL-equivalent result from either injectable alone is misrepresenting what these products can do. Both improve appearance and skin quality significantly; neither replaces a surgical BBL or a Sculptra protocol of 10+ vials. See our dedicated non-surgical BBL page for more.
Radiesse is formulated with lidocaine, so most patients describe the injection as pressure rather than sharp pain. Kelly also applies topical anesthetic and offers the option of a blunt-tip microcannula for larger areas like the jawline, which reduces bruising and discomfort meaningfully compared with a sharp needle. Most patients tolerate Radiesse appointments very comfortably.
Most patients return to normal activity the same day. Mild swelling is expected for 24–48 hours and resolves on its own. Bruising, if it occurs, typically resolves within 5–7 days. Avoid strenuous exercise, saunas, and direct sun for 24–48 hours, and avoid sleeping with pressure on treated areas the first night.
For hand or neck hyperdilute treatments, gentle self-massage of the area may be recommended in the days that follow — Kelly will walk you through the exact protocol for your specific treatment.
No. Unlike hyaluronic acid fillers, which can be dissolved with hyaluronidase, Radiesse cannot be reversed once placed. This is one of the reasons Radiesse should be placed only by an injector with deep anatomical training, a conservative approach, and the patience to layer slowly. It is also why we generally counsel against Radiesse for patients who change their aesthetic preferences frequently — an HA filler will give you more flexibility.
The flip side: Radiesse’s lack of reversibility is also what makes it last so much longer than HA fillers. Trade-offs.
Most healthy adults seeking structural facial volumization, jawline definition, hand rejuvenation, or skin-quality improvement on the neck/décolleté/body are good candidates. Radiesse is FDA-approved for adults 35+ for facial use and for hand rejuvenation, though it can be appropriate for younger patients with specific structural goals.
You are not a candidate if you are pregnant or breastfeeding, have an active skin infection at the planned injection site, have a known hypersensitivity to any component of Radiesse, or have a history of severe allergic reactions or anaphylaxis. Disclose your full medical and allergy history at consultation.
Yes — and often should be. Radiesse for the lower face (jawline, chin) combines naturally with neuromodulator (Botox, Dysport, or Xeomin) for the upper face, and with HA filler for lips or tear troughs. Hyperdilute Radiesse for the neck pairs beautifully with medical microneedling or RF for the same area. Sculptra and Radiesse can also be sequenced in the same treatment plan — Sculptra for broad facial rejuvenation, Radiesse for focal structural lift. Sequencing matters; Kelly will plan it out at consultation.
1000 5th Street, Suite 414, Miami Beach, FL 33139 — in the South of Fifth (SoFi) district at the southern tip of Miami Beach. We’re 8 minutes from Brickell, 10 from Mid-Beach, 19 from Bal Harbour. $4/hr in the attached garage; free street parking is available around the building during business hours (one nearby zone is metered). Phone: (786) 529-1860. Hours: Monday–Friday 10am–6pm, Saturday 10am–2pm.
